Journal: International Journal of Biometeorology

Article Title: Dissipation of excess excitation energy of the needle leaves in Pinus trees during cold winters

doi: 10.1007/s00484-016-1182-3

Figure Lengend Snippet: The comparison of chlorophyll fluorescence parameters of needles in Pinus trees between in cold winter and summer

Article Snippet: The plants used in this study were specimens of Pinus koraiensis (height 7.2–8.5 m, diameter at breast height 16.3–18.1 cm, tree age 48 years), Pinus tabulaeformis (height 10.1–11.3 m, diameter at breast height 26.9–29.4 cm, tree age 31 years), and Pinus armandi (height 7.9–9.1 m, diameter at breast height 21.0–23.3 cm, tree age 41 years) growing in the botanic garden of Shenyang Agricultural University, Shenyang city, Liaoning Province, China (41° 82′ N, 123° 56′ E).

Techniques: Comparison, Fluorescence

Journal: European Journal of Cancer

Article Title: AGIHO guideline on evidence-based management of COVID-19 in cancer patients: 2022 update on vaccination, pharmacological prophylaxis and therapy in light of the omicron variants

doi: 10.1016/j.ejca.2022.11.030

Figure Lengend Snippet: Recommendations on prophylaxis against COVID-19 in cancer patients.

Article Snippet: Remdesivir applied intravenously for 3 days was assessed as early therapy against placebo in the similarly designed PINETREE RCT, resulting in an 87% relative risk reduction of COVID-related hospitalisation or death in unvaccinated high-risk outpatients with COVID-19 within 7 days of symptom onset [ ].

Techniques: Infection, Clinical Proteomics

Journal: European Journal of Cancer

Article Title: AGIHO guideline on evidence-based management of COVID-19 in cancer patients: 2022 update on vaccination, pharmacological prophylaxis and therapy in light of the omicron variants

doi: 10.1016/j.ejca.2022.11.030

Figure Lengend Snippet: Recommendations on treatment of cancer outpatients with mild COVID-19 (WHO score 1–3).

Article Snippet: Remdesivir applied intravenously for 3 days was assessed as early therapy against placebo in the similarly designed PINETREE RCT, resulting in an 87% relative risk reduction of COVID-related hospitalisation or death in unvaccinated high-risk outpatients with COVID-19 within 7 days of symptom onset [ ].

Techniques: Clinical Proteomics

Journal: European Journal of Cancer

Article Title: AGIHO guideline on evidence-based management of COVID-19 in cancer patients: 2022 update on vaccination, pharmacological prophylaxis and therapy in light of the omicron variants

doi: 10.1016/j.ejca.2022.11.030

Figure Lengend Snippet: Recommendations on treatment of hospitalized cancer patients with moderate to severe COVID-19 (WHO score 4–9).

Article Snippet: Remdesivir applied intravenously for 3 days was assessed as early therapy against placebo in the similarly designed PINETREE RCT, resulting in an 87% relative risk reduction of COVID-related hospitalisation or death in unvaccinated high-risk outpatients with COVID-19 within 7 days of symptom onset [ ].

Techniques: Clinical Proteomics, Bioprocessing

Journal: Metabolites

Article Title: Molnupiravir: A Versatile Prodrug against SARS-CoV-2 Variants

doi: 10.3390/metabo13020309

Figure Lengend Snippet: Comparison of antiviral therapeutics for COVID-19.

Article Snippet: Important clinical trial , , MOVe-OUT , EPIC-HR , PINETREE , NCT04434248, NCT04529499 , [ ] .

Techniques: Comparison, Protease Inhibitor, Clinical Proteomics, In Vitro

Journal: G3: Genes|Genomes|Genetics

Article Title: Performance of Seven Tree Breeding Strategies Under Conditions of Inbreeding Depression

doi: 10.1534/g3.115.025767

Figure Lengend Snippet: Estimates of inbreeding depression in relation to the additive genetic standard deviation (µ D /σ A ) for growth traits calculated from literature assuming additive coefficients of variation ( CV A ) of 10% for tree height and diameter and 20% for volume ( Cornelius 1994 )

Article Snippet: Pinus elliottii , 2.4–5.2 , 3.7–9.4 , 3.6–8.2 , Matheson et al. 1995 .

Techniques: Standard Deviation

Journal: Bioinformatics

Article Title: Pinetree: a step-wise gene expression simulator with codon-specific translation rates

doi: 10.1093/bioinformatics/btz203

Figure Lengend Snippet: Design and example output of Pinetree. Pinetree is a generic gene expression simulator that tracks individual RNA polymerases on DNA, and ribosome and RNases on mRNA transcripts. RNases are optional and Pinetree can simulate gene expression with or without transcript degradation. (A) A specialized set of reactions mediates binding and movement of ribosomes, RNA polymerases and RNases. These reactions convert molecules from a species pool into individually modeled ribosomes, polymerases, and RNases. (B) Pinetree tracks individual ribosomes and RNA polymerases on transcripts and DNA, respectively. Lightning bolts represent potential collisions. Ribosomes may begin translation before a full transcript has been synthesized by the RNA polymerases. Likewise, an RNase may begin degrading an RNA transcript before the polymerase has synthesized the full transcript. Together, Pinetree allows the end user to define arbitrary reactions between molecules in the free species pool, while still modeling transcription and translation at the single-molecule level. (C) Simulation of a three-gene plasmid with one gene (proteinY) recoded to use rare codons. No RNases are present in this simulation, so no degradation occurs. Translation of proteinY is slower than that of proteinX and rnapol. (D) Ribosome densities on the transcript of proteinY are higher in the recoded gene than in the wild-type. The recoded gene has lower per-codon translation rates than that of the wild-type

Article Snippet: RNases are optional and Pinetree can simulate gene expression with or without transcript degradation. ( A ) A specialized set of reactions mediates binding and movement of ribosomes, RNA polymerases and RNases.

Techniques: Gene Expression, Binding Assay, Synthesized, Plasmid Preparation